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Writer's picturetarunaffy

What are the Advantages and Disadvantages of Soft Gelatin Capsules

There are many dosage forms, soft gelatin capsules are one of them, whose outer covering is made up of gelatin and other ingredients and this covering is encapsulated with inner medicament in the form of semi-solid or liquid.


Advantages of Soft Gelatin Capsules

  • As compared to other mode of administration soft gelatin capsules are administered through oral route, very easy to swallow.

  • Soft gelatin capsules are free from taste and odour.

  • Soft gelatin capsules are in sealed form so they protect the inner fill from oxidation and degradation.

  • Opaque soft gelatin capsules also protect the inner fill from UV radiation and photo sensitive products.

  • It enhance patient compliance due to its elegant appearance.

  • Suitable for medicaments like semisoli, oils, liquid forms.

  • Soft gelatin capsules increase the bioavailability of API.

Disadvantage of Soft Gelatin Capsules

  • Soft gelatin capsules having difficulties in dealing with water soluble materials.

  • Soft gelatin capsules are highly sensitive to moisture.

  • Soft gelatin capsules having difficulties in dealing with efflorescent materials.

  • Soft gelatin capsules having difficulties in dealing with deliquescent materials.

  • As gelatin is obtained from animal source so soft gelatin capsules are not suitable for people belongs to vegetarian group.

  • Manufacturing procedure of soft gelatin capsules is complex as compared to other dosage forms.

Soft gelatin capsules are more preferable than hard gelatin capsules, but in India, there are very less manufacturers of Soft gelatin capsules, sometimes it leads to problem of unavailability of soft gelatin capsules. Companies like Affy group provide a platform to overcome unavailability of soft gel capsules they engaged in soft gelatin capsules manufacturing in India, and provide us varieties of soft gelatin capsules like phosphodiesterase, multivitamins, multiminerals , retinoids, gabapentinoid, food supplements (cod liver oil , primrose oil) etc.


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